I've posted these tools to my twitter account but am now putting them here for easier access and to show the feedback I received. (Note: Some of these tools are not free or Windows specific ) (Note: These apps are just my personal opinion and I did not receive compensation for recommending them) Add your feedback to the comments!
#1 Fences - desktop organizer
#2 twhirl - Twitter client - Less complicated than tweetdeck
#3: Beyond Compare - best comparison tool I've ever used. Period!
#4: MagicDisc - mounting ISOs with greatest of ease
#5: DeskSpace - virtual desktops - just found the other day, best i've used so far
#6: LogMeIn - connect to your remote machine from PC, Mac, and smartphones
#7 - NotePad++ - my fav alternative to the original notepad
#8: Paint.NET - superior to mspaint in every way
#9: Pandora - the invaluable distraction blocker
#10: RD Tabs - tabbed remote desktop organizer - I couldnt live without this!
#11: UltraMon - multi-monitor organizer
#12: PowerCommands for Visual Studio - adds more functionality to the VS IDE
#13: WizMouse - get mouse wheel scrolling in any window with no clicking
#14: Xobni - adds better email search and organization to your inbox
#16: OneNote - best note/screenshot taker that natively integrates with Microsoft Office